GOKMEN AKTAS compressed

Assoc. Prof. Gökmen Aktaş, M.D.

MedicalPoint Gaziantep Hospital
Medical Oncology

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Name

Education and Expertise

  • Marmara University Faculty of Medicine – Medical Education – Medicine
  • Marmara University Faculty of Medicine, Department of Internal Medicine – Specialization – Medicine
  • Gaziantep University Faculty of Medicine, Department of Medical Oncology – Subspecialty – Medicine

Experience

  • Kahramanmaraş Sütçü İmam University Faculty of Medicine, Department of Internal Medicine, Division of Medical Oncology – Faculty Member – Head of Medical Oncology Division

Professional Memberships

  • Turkish Medical Oncology Society
  • European Society for Medical Oncology
  • Gaziantep Medical Chamber

Research Publications

Articles published in international peer-reviewed journals: Articles published in international peer-reviewed journals (SCI, SSCI, Arts and Humanities)

  • Kus T, Aktas G, Sevinc A, Kalender ME, Camci C. Could erlotinib treatment lead to acute cardiovascular events in patients with lung adenocarcinoma after chemotherapy failure? Onco Targets Ther. 2015 Jun 5;8:1341-3. doi: 10.2147/OTT.S84480.

  • Kus T, Aktas G, Kalender ME, Sevinc A, Kul S, Suner A, Ulker E, Camci C. Taxane-induced peripheral sensorial neuropathy in cancer patients is associated with duration of diabetes mellitus: a single-center retrospective study. Support Care Cancer. 2016 Mar;24(3):1175-9. doi: 10.1007/s00520-015-2898-z.

  • Kus T, Aktas G, Alpak G, Kalender ME, Sevinc A, Kul S, Temizer M, Camci C. Efficacy of venlafaxine for the relief of taxane and oxaliplatin-induced acute neurotoxicity: a single-center retrospective case-control study. Support Care Cancer. 2016 May;24(5):2085-91. doi: 10.1007/s00520-015-3009-x.

  • Kus T, Aktas G, Sevinc A, Kalender ME, Yilmaz M, Kul S, Oztuzcu S, Oktay C, Camci C. Prognostic impact of initial maximum standardized uptake value of (18)F-FDG PET/CT on treatment response in patients with metastatic lung adenocarcinoma treated with erlotinib. Onco Targets Ther. 2015 Dec 15;8:3749-56. doi: 10.2147/OTT.S94945.

  • Kus T, Aktas G, Kalender ME, Tutar E, Ulker E, Camci C. Complete response of a recurrent-metastatic liposarcoma with dedifferentiated histological features following the administration of trabectedin and review of literature. J Cancer Res Ther. 2015 Oct-Dec;11(4):974-6. doi: 10.4103/0973-1482.158032. Review.

  • Kus T, Aktas G, Kalender ME, Sari I, Ulker E, Camci C. Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review. Oncol Lett. 2016 Apr;11(4):2801-2805.

  • Aktas G, Kus T, Kalender ME, Sevinc A, Camci C, Kul S. Survival analysis in second-line and third-line chemotherapy with irinotecan followed by topotecan or topotecan followed by irinotecan for extensive-stage small-cell lung cancer patients: a single-center retrospective study. Onco Targets Ther. 2016 Apr 1;9:1921-6. doi: 10.2147/OTT.S101390.

  • Kus T, Aktas G, Kalender ME, Demiryurek AT, Ulasli M, Oztuzcu S, Sevinc A, Kul S, Camci C. Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel. Onco Targets Ther. 2016 Aug 12;9:5073-80. doi: 10.2147/OTT.S106574.

  • Suner A, Buyukhatipoglu H, Aktas G, Kus T, Ulasli M, Oztuzcu S, Kalender ME, Sevinc A, Kul S, Camci C. Polymorphisms in the MTHFR gene are associated with recurrence risk in lymph node-positive breast cancer patients. Onco Targets Ther. 2016 Sep 9;9:5603-9. doi: 10.2147/OTT.S104890.

  • Aktas G, Kus T, Kalender ME, Kervancıoglu AS, Sevinc A, Kul S, Camci C. Sorafenib with TACE improves the survival of hepatocellular carcinoma patients with more than 10 cm tumor: a single-center retrospective study. JBUON 2017; 22: 150-156

  • Kus T, Aktas G, H Ekici, G Elboğa, S Djamgöz. Illness perception is a strong parameter on anxiety and depression scores in early-stage breast cancer survivors: a single-center cross-sectional study of Turkish patients. Support Care Cancer. 2017 May 26.

  • Kus T, Aktas G, H Ekici, G Elboğa. Comparison of distress in breast cancer survivors treated with different adjuvant endocrine therapies: a single-centre cross-sectional study. Psychiatry and Clinical Psychopharmacology, DOI: 10.1080/24750573.2017.1342316

  • Aktas G, Kus T, Metin T, Kervancioglu S, Elboga U. Long-term survival with transarterial chemoembolization and radioembolization in a patient with cancers of unknown primary. Onco Targets Ther. 2018 Apr 4;11:1885-1889. doi: 10.2147/OTT.S153122.

  • Kus T, Cinkir HY, Aktas G, Abali H. Hepatosteatosis may predict late recurrence of breast cancer: A single-center observational study. Curr Probl Cancer. 2019 Jan 23. pii: S0147-0272(18)30398-2. doi: 10.1016/j.currproblcancer.2019.01.002.

  • Aktas G, Kus T, Balkan A, Metin T, Gulsen MT, Abali H. Prognostic factors in patients with advanced extrahepatic cholangiocarcinoma: A single center experience. Medicine (Baltimore). 2019 Feb;98(8):e14556. doi: 10.1097/MD.0000000000014556.

Papers Presented at International Scientific Meetings and Published in Proceedings:

  • T Kus, A Sevinc, G Aktas, S Oztuzcu, ME Kalender, C Camci. Predictive Value of Initial Maximal Standardized Uptake Value of 18F-FDG PET/CT in Patients with Lung Adenocarcinoma Treated with Erlotinib. Journal of Thoracic Oncology 10 (9), S585-S585. Poster Presentation.

  • ME Kalender, F Bulbul, G Aktas, T Kus, B Okyar, O Balakan, C Camci. Awareness of cancer diagnosis in Turkish patients can increase anxiety and depression: is it true? Annals of Oncology 27 (suppl 6), 1504P. Poster Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, C Camci. Relation of inter-individual genetic polymorphism with taxanes-induced cytopenia and hepatotoxicity. SANKO University Innovation in Medicine Summit-2, 5th-7th, Gaziantep, Turkey. Oral Presentation.

  • T Kus, G Aktas, T Yildiz, ME Kalender, A Sevinc, C Camci. P53 and ERCC1 gene polymorphisms can predict the recurrence risk of breast cancer. SANKO University Innovation in Medicine Summit-2, 5th-7th, Gaziantep, Turkey. Oral Presentation.

  • A Balkan, T Kus, G Aktas, T Metin, MT Gulsen. Factors Predicting the Overall Survival and Effectiveness of Endoscopic Retrograde Cholangiopancreatography in Patients with Extrahepatic Cholangiocarcinoma After Progression. ICONS 2017, Abstract number SB20, Antalya, Turkey. Oral Presentation.

  • T Kus, UY Arslan, AM Sedef, G Aktas, F Kose, HY Cinkir, NY Ozdemir. Factors predicting peritoneal recurrence in resected gastric cancer: Prediction of sub-groups who may benefit from adjuvant intraperitoneal treatment modalities. 2nd ICONS 2018, S32, Antalya, Turkey. Oral Presentation.

Chapters in National/International Books:

  • Aktaş G. Treatments Targeting Cancer Stem Cells. Current Approaches in Oncology 1. 2018. Akademisyen Publishing House. ISBN: 978-605-258-374-6.

  • Aktas G. Breast Cancer Treatment. Akademisyen Publishing House Scientific Research Book, Oncology, 2018. ISBN: 978-605-258-068-4.

Articles Published in National Peer-Reviewed Journals:

  • G Aktas, T Kus, ME Kalender, K Bakir, C Camci. A Patient with Organizing Pneumonia Development During the Use of Capecitabine Maintenance Treatment for Gastric Cancer. Respiratory Case Reports. 2016; 5(1): 10-14.

  • S Kimyon, A Mete, T Kus, Y Tuylu, KE Er, G Aktas, C Pamukcu. Giant Conjunctival Melanoma with Breast Cancer and Chronic Lymphocytic Leukemia: A Case Report and Mini-Review of the Literature. Turkiye Klinikleri Journal of Ophthalmology. doi: 10.5336/ophthal.2016-52701.

  • Kus T, Aktas G. Maintenance treatment with gemcitabine has a promising activity on metastatic bladder cancer survival. Turkish Journal of Urology August 2017 DOI: 10.5152/tud.2017.24478.

  • Elboga G, Aksoy G, Kus T, Karayagmurlu E, Aktas G, Sahin S, Altindag A. 5-fluorouracil-induced manic episode in patients with colon cancer: A case report and literature review. Annals of Medical Research 2019;26(6):1123-5. DOI: 10.5455/annalsmedres.2019.03.138.

Papers Presented at National Scientific Meetings and Published in Proceedings:

  • T Kus, A Sevinc. Hepatocellular carcinoma developing in a patient with metastatic renal cell carcinoma treated with sunitinib. 5th Turkish Medical Oncology Congress. March 19-23, 2014, Antalya, Turkey. Poster Presentation.

  • T Kus, G Aktas, C Camci, ME Kalender. Case of organizing pneumonia developing in a patient with stage IV gastric cancer using maintenance capecitabine therapy. 21st National Cancer Congress. April 22-26, 2015, Antalya, Turkey. Poster Presentation.

  • T Kus, G Aktas, C Camci, ME Kalender. Complete response in metastatic dedifferentiated liposarcoma after trabectedin therapy. 21st National Cancer Congress. April 22-26, 2015, Antalya, Turkey. Poster Presentation.

  • T Kus, G Aktas, A Sevinc, ME Kalender, C Camci. Effect of diabetes mellitus on acute sensory neuropathy development in patients receiving paclitaxel and docetaxel: single-center retrospective analysis. 21st National Cancer Congress. April 22-26, 2015, Antalya, Turkey. Oral Presentation.

  • T Kus, G Alpak, G Aktas, A Sevinc, ME Kalender, C Camci. Symptomatic improvement rates with venlafaxine treatment in patients developing acute peripheral sensory neurotoxicity during taxane and oxaliplatin therapy: case-control retrospective analysis. 21st National Cancer Congress. April 22-26, 2015, Antalya, Turkey. Oral Presentation.

  • T Kus, G Aktas, A Sevinc, ME Kalender, C Camci. Predictive value of baseline PET-CT SUVmax in treatment response to erlotinib in lung adenocarcinoma: single-center retrospective analysis. 21st National Cancer Congress. April 22-26, 2015, Antalya, Turkey. Poster Presentation.

  • G Aktas, T Kus, ME Kalender, I Sari, E Ulker, C Camci. Collision tumor of primary adenocarcinoma and follicular lymphoma in the cecum. Immuno-oncology and Targeted Cancer Therapy Congress. May 13-17, 2015. Antalya, Turkey. Poster Presentation.

  • T Kus, G Aktas, ME Kalender, AT Demiryurek, M Ulasli, K Tanrıverdi, S Oztuzcu, A Sevinc, C Camci. Effect of CYP3A4 and ABCB1 gene polymorphisms on taxane-induced neurotoxicity in breast cancer patients. 6th Turkish Medical Oncology Congress. March 23-27, 2016. Oral Presentation.

  • G Aktas, H Buyukhatipoglu, T Kus, B Okyar, S Alkan, ME Kalender, A Sevinc, C Camci. Discordance in ER, PR, and Her2 expression between primary tumor and recurrent/metastatic lesions in breast cancer patients and its impact on survival. 6th Turkish Medical Oncology Congress, March 23-27, 2016. Poster Presentation.

  • A Suner, H Buyukhatipoglu, G Aktas, T Kus, M Ulasli, S Oztuzcu, ME Kalender, A Sevinc, S Kul, C Camci. Effect of MTHFR gene polymorphism on recurrence risk in lymph node-positive breast cancer patients. 6th Turkish Medical Oncology Congress, March 23-27, 2016. Poster Presentation.

  • T Kus, G Aktas, F Bulbul, ME Kalender, C Camci. Correlation between diagnosis stage, diagnosis duration, psychosocial support, and depression/anxiety levels in breast cancer patients in remission. 12th National Medical Oncology Congress. September 16-20, 2015. İzmir, Turkey. Oral Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, C Camci. Response rates in second- and third-line irinotecan/topotecan chemotherapy in small-cell lung cancer patients: single-center retrospective analysis. 12th National Medical Oncology Congress. September 16-20, 2015. İzmir, Turkey. Poster Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, A Kalem, C Camci. Role of gene polymorphisms involved in drug metabolism in predicting chemotherapy response in metastatic colorectal carcinoma patients. 8th Gastrointestinal Oncology Congress. April 8-9, 2016. Gaziantep, Turkey. Oral Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, C Camci. Retrospective survival analysis of hepatocellular carcinoma patients with stage A-B receiving sorafenib versus those not receiving sorafenib. 8th Gastrointestinal Oncology Congress. April 8-9, 2016. Gaziantep, Turkey. Poster Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, C Camci. Experiences with FOLFIRINOX in metastatic gallbladder and cholangiocellular carcinoma patients under standard treatment regimens: retrospective survival analysis. 8th Gastrointestinal Oncology Congress. April 8-9, 2016. Gaziantep, Turkey. Poster Presentation.

  • G Aktas, T Kus, ME Kalender, A Sevinc, C Camci. Retrospective survival analysis of cisplatin-gemcitabine versus FOLFIRINOX in unresectable periampullary carcinoma patients. 8th Gastrointestinal Oncology Congress. April 8-9, 2016. Gaziantep, Turkey. Poster Presentation.

  • T Kus, G Aktas. Comparison of distress in breast cancer survivors treated with different adjuvant endocrine therapies: A single-center cross-sectional study. P-355. April 19-23. Antalya, Turkey. 22nd National Cancer Congress. Poster Presentation.

  • T Kus, G Aktas. Assessment of platelet reactivity after anthracycline-based chemotherapy via mean platelet volume: Does it act on anthracycline-induced cardiotoxicity? P-399. April 19-23. Antalya, Turkey. 22nd National Cancer Congress. Poster Presentation.

  • T Kus, G Aktas. Maintenance treatment with gemcitabine has promising activity on bladder cancer survival. P-467. April 19-23. Antalya, Turkey. 22nd National Cancer Congress. Poster Presentation.

  • A Balkan, T Kus, G Aktas, T Metin, MT Gulsen, H Abali. Factors predicting chemotherapy eligibility rate in patients with extrahepatic cholangiocarcinoma after progression: A retrospective study. EP-202. March 21-25, 2018. Antalya, Turkey. 7th Turkish Medical Oncology Congress. Poster Presentation.

  • T Kus, HY Cinkir, G Aktas, H Abali. Investigation of the predictive role of hepatosteatosis on recurrence and pattern in breast cancer: single-center retrospective observational study. SSB-29. October 31-November 4, 2018. Antalya, Turkey. 2nd National Immunotherapy and Oncology Congress. Oral Presentation.

  • HY Cinkir, T Kus. Prognostic effect of systemic inflammatory and nutritional parameters before tyrosine kinase inhibitor therapy in elderly patients with metastatic renal cell carcinoma diagnosis. SB-09. November 9-11, 2018. Antalya, Turkey. 3rd Geriatric Oncology Congress. Oral Presentation.

Other Publications:

  • (Works not falling under the above categories and to be specified here.)

  • Kus T, Aktas G, Kalender ME, Sevinc A, Camci C. Comparison of FOLFIRINOX chemotherapy with other regimens in patients with biliary tract cancers: a retrospective study. Journal of Gastrointestinal Cancer. June 2017;48(2):170-175. doi: 10.1007/s12029-016-9880-y.

  • Kus T, Kalender ME, Aktas G, Suner A, Camci C. Atypical presentation of disseminated intravascular coagulation with synchronous peripheral venous thromboembolism and arterial gangrene in a pancreatic cancer patient: a case report. Journal of Pancreas (JOP). March 20, 2015;16(2):195-7. doi: 10.6092/1590-8577/2943.

  • Kus T, Aktas G, Sevinc A, Oktay C, Kalender ME, Camci C. Tyrosine kinase inhibitors improve parenchymal findings of liver cirrhosis in a patient exhibiting concomitant hepatocellular carcinoma and renal cell cancer. Molecular and Clinical Oncology. February 2016;4:290-292.

Courses and Certificates:

  • TOD Sarcomas and Dermatologic Cancers Course (Istanbul 2014)

  • 10th National Oncological Research Workshop (2014)

  • Advanced GCP (Good Clinical Practice) Course (2015)

  • TOD Hematologic Malignancies and Lymphoma Course (2015)

  • 12th National Oncological Research Workshop (Antalya, 2016)

  • TOD Gynecological Cancers Training Course (Istanbul 2016)

  • TOD Head and Neck and CNS Cancers Training Course (2016)

  • Clinical Oncology Society / Basic Oncology Course 2017 (Adana) (SPEAKER)

  • 5th Turkish Medical Oncology Congress (2014)

  • GIOK 2016 (Gastrointestinal Oncology Congress) (Gaziantep)

  • 21st National Cancer Congress 2015 (Antalya)

  • 2nd Immuno-Oncology and Targeted Cancer Therapies Congress 2015 (Antalya)

  • Symposium on Supportive Treatments in Cancer 2015

  • Best of ASCO 2015 Symposium

  • 6th Turkish Medical Oncology Congress (2016)

  • 3rd Immuno-Oncology and Targeted Cancer Therapies Congress 2016 (Antalya)

  • 22nd National Cancer Congress 2017 (Antalya)

  • ASCO 2018 Congress (Chicago, USA)

  • National Immunotherapy and Oncology Congress 2017 (Antalya) (SPEAKER)

  • 7th International Gastrointestinal Cancer Conference 2017 (Istanbul, Turkey)

  • 1st Oncology Perspective with Youth Congress 2018 (Antalya, Turkey)

  • 7th Turkish Medical Oncology Congress 2018 (Antalya, Turkey)

  • 2nd International Congress on Oncological Sciences (ICONS) 2018 (Antalya, Turkey)

  • 2nd National Immunotherapy and Oncology Congress 2018 (Antalya, Turkey)

  • ESMO 2019 (Barcelona, Spain)